Which organism is NOT typically required to be targeted for high-level disinfection?

High-level disinfection is a critical process aimed at eliminating microorganisms that pose a significant risk of infection, particularly in healthcare settings. Among the options presented, bacterial spores are generally not included in the routine high-level disinfection targets. This is because bacterial spores, such as those produced by Clostridium difficile and some other bacteria, are exceptionally resistant to disinfectants and require sterilization methods to ensure they are adequately eradicated.

High-level disinfection typically targets fungi, viruses, and mycobacteria, which can be effectively eliminated by the appropriate use of high-level disinfectants. Fungi and viruses can cause infections and are generally more susceptible to disinfection processes. Mycobacteria, such as Mycobacterium tuberculosis, also require thorough disinfection due to their potential to cause serious infections and their relative resistance compared to other organisms.

Thus, the focus on bacterial spores highlights their unique resistance and the need for more stringent sterilization methods rather than disinfection, making them the organism that is typically not required to be targeted for high-level disinfection.