Which of the following statements regarding tuberculosis is NOT considered true?

The selected statement does not accurately reflect the safety profile of the medications used in the treatment of tuberculosis (TB). Isoniazid (INH) and rifampin are first-line agents in the management of TB and are essential for effective treatment. While it is true that these medications can have side effects, including elevations in serum aminotransferases, significant nephrotoxicity is not typically associated with their use.

The potential for liver toxicity is more notable with INH due to its hepatotoxic effects, particularly in certain populations or with advanced age. However, nephrotoxicity is not a common or recognized issue associated with INH or rifampin. Patients on these medications must be monitored for liver function, but the emphasis on nephrotoxic effects is misleading and incorrect.

In contrast, the other statements accurately reflect clinical practices and precautions necessary when dealing with active TB patients. For instance, urgent care considerations underscore the importance of managing active TB in a controlled environment, emphasizing isolation and protective measures. Similarly, the handling of patients producing negative sputum accurately describes their non-infectious status, allowing for more standard care protocols to be applied.