Which of the following local delivering devices does not contain any tetracycline or tetracycline derivative?

Periochip is the local delivering device that does not contain any tetracycline or tetracycline derivative. Instead, it is composed of chlorhexidine gluconate, an antimicrobial agent known for its effectiveness in treating periodontal disease. The design of Periochip allows for the sustained release of chlorhexidine over an extended period, helping to control bacterial growth and promoting periodontal healing.

In contrast, Arestin and Atridox both utilize forms of tetracycline for their antibacterial properties. Arestin contains minocycline, a derivative of tetracycline, while Atridox delivers doxycycline, another tetracycline derivative. Periostat, although it is an oral medication rather than a localized delivery device, also contains doxycycline, thereby linking it to tetracycline derivatives as well.

Understanding the distinction between these different products and their active ingredients is essential in selecting appropriate treatments for periodontal conditions.