Which factor is least likely to cause pain on an edentulous ridge in patients wearing removable prostheses?

The presence of one or more resin spicules is least likely to cause pain on an edentulous ridge in patients wearing removable prostheses because these spicules are generally small irregularities or rough areas that can occur during the processing of dentures. While resin spicules can certainly cause discomfort, particularly if they are large or protruding, their size and isolated nature often make them less impactful compared to other factors that can contribute to pain and discomfort in the prosthesis-wearing experience.

On the other hand, malocclusion, excessive occlusal vertical dimension, and an inaccurate denture base are broader issues that can lead to significant discomfort. Malocclusion can cause uneven forces on the ridge, potentially leading to soreness or irritation. Excessive occlusal vertical dimension may put undue pressure on the oral tissues, resulting in pain both at rest and during function. An inaccurate denture base, meanwhile, can lead to improper fitting, causing instability and irritation of the underlying ridge, which may ultimately be more prevalent in producing pain than isolated resin spicules.