Which agent is often used alongside fluoride in desensitizing toothpaste?

Arginine is frequently used in conjunction with fluoride in desensitizing toothpaste due to its ability to effectively alleviate tooth sensitivity. It is an amino acid that works by promoting the deposition of calcium and phosphate ions on the tooth surface, which can help to strengthen enamel and block exposed dentinal tubules that are responsible for sensitivity. This synergy enhances the protective effects of fluoride, allowing for more effective remineralization of the enamel and improved management of sensitivity.

The inclusion of arginine in toothpaste is particularly beneficial for patients with dentin hypersensitivity, as it not only aids in sealing the tubules but also supports the natural remineralization process alongside fluoride treatment, providing a dual action in enhancing tooth health.