What condition may result from excessive epinephrine administration in hyperthyroid patients?

Excessive administration of epinephrine, especially in individuals with hyperthyroidism, can lead to thyrotoxicosis. This condition occurs due to an increased release of thyroid hormones, which can be exacerbated by adrenergic stimulation. In hyperthyroid patients, the presence of excess thyroid hormones already heightens metabolic activity, increases heart rate, and stimulates the sympathetic nervous system. The administration of epinephrine can further amplify these effects, leading to severe manifestations associated with an excess of thyroid hormones in the body.

Recognizing thyrotoxicosis is important because it can precipitate various complications such as increased heart rate (tachycardia), anxiety, tremors, and in severe cases, a thyroid storm, which is a life-threatening exacerbation of the condition. The link between epinephrine administration and this exacerbation in hyperthyroid patients explains why thyrotoxicosis is the most relevant condition in this context.

The other conditions, while they may be serious, are not directly induced by the interaction of epinephrine and hyperthyroidism in the same manner as thyrotoxicosis.